Lineage for d2todd1 (2tod D:37-43,D:284-410)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2798607Fold b.49: Domain of alpha and beta subunits of F1 ATP synthase-like [50614] (4 superfamilies)
    barrel, closed; n=6, S=8; greek-key
    Many cradle-loop superfamilies may be homologous, according to PubMed 18457946
  4. 2798988Superfamily b.49.2: Alanine racemase C-terminal domain-like [50621] (2 families) (S)
    the barrel is decorated with additional structures
  5. 2799024Family b.49.2.3: Eukaryotic ODC-like [88683] (2 proteins)
    barrel is open with strands 4 and 5 having swapped their positions, compared to the alanine racemase barrel
  6. 2799041Protein Eukaryotic ornithine decarboxylase (ODC) [50625] (3 species)
  7. 2799047Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [50628] (5 PDB entries)
    Uniprot P07805
  8. 2799051Domain d2todd1: 2tod D:37-43,D:284-410 [26492]
    Other proteins in same PDB: d2toda2, d2todb2, d2todc2, d2todd2
    complexed with dmo, plp; mutant
    missing some secondary structures that made up less than one-third of the common domain

Details for d2todd1

PDB Entry: 2tod (more details), 2 Å

PDB Description: ornithine decarboxylase from trypanosoma brucei k69a mutant in complex with alpha-difluoromethylornithine
PDB Compounds: (D:) protein (ornithine decarboxylase)

SCOPe Domain Sequences for d2todd1:

Sequence, based on SEQRES records: (download)

>d2todd1 b.49.2.3 (D:37-43,D:284-410) Eukaryotic ornithine decarboxylase (ODC) {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gdpffvaXftlavnviakkvtpgvqtdvgahaesnaqsfmyyvndgvygsfncilydhav
vrplpqrepipneklypssvwgptcdgldqiveryylpemqvgewllfedmgaytvvgts
sfngfqsptiyyvvs

Sequence, based on observed residues (ATOM records): (download)

>d2todd1 b.49.2.3 (D:37-43,D:284-410) Eukaryotic ornithine decarboxylase (ODC) {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gdpffvaXftlavnviakkvtpaqsfmyyvndgvygsfncilydhavvrplpqrepipne
klypssvwgptcdgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyv
vs

SCOPe Domain Coordinates for d2todd1:

Click to download the PDB-style file with coordinates for d2todd1.
(The format of our PDB-style files is described here.)

Timeline for d2todd1: