SCOP 1.75: Domain d1tfxb_: 1tfx B:

Lineage for d1tfxb_ (1tfx B:)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Trypsin(ogen) [50515] (9 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [50517] (23 PDB entries)
   Uniprot P00761 9-231
   Uniprot P00761
   Uniprot P00761 9-231 ! Uniprot P00761

8. Domain d1tfxb_: 1tfx B: [25973]
   Other proteins in same PDB: d1tfxc_, d1tfxd_
   complexed with ca

Details for d1tfxb_

PDB Entry: 1tfx, 2.6 Å

PDB Description: complex of the second kunitz domain of tissue factor pathway inhibitor with porcine trypsin

PDB Compounds: (B:) Trypsin

SCOP Domain Sequences for d1tfxb_:

Sequence; same for both SEQRES and ATOM records:

>d1tfxb_ b.47.1.2 (B:) Trypsin(ogen) {Pig (Sus scrofa) [TaxId: 9823]}
ivggytcaansipyqvslnsgshfcggslinsqwvvsaahcyksriqvrlgehnidvleg
neqfinaakiithpnfngntldndimliklsspatlnsrvatvslprscaaagteclisg
wgntkssgssypsllqclkapvlsdssckssypgqitgnmicvgfleggkdscqgdsggp
vvcngqlqgivswgygcaqknkpgvytkvcnyvnwiqqtiaan

Timeline for d1tfxb_:

• d1tfxb_ first appeared (with stable ids) in SCOP 1.55
  
• d1tfxb_ appears in SCOP 1.73
  
• d1tfxb_ appears in SCOPe 2.01
  
• d1tfxb_ appears in the current release, SCOPe 2.08