SCOPe 2.07: Domain d4dgld_: 4dgl D:

Lineage for d4dgld_ (4dgl D:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (180 PDB entries)

8. Domain d4dgld_: 4dgl D: [251442]
   Other proteins in same PDB: d4dgla_, d4dglb_
   automated match to d3wara_
   complexed with zn

Details for d4dgld_

PDB Entry: 4dgl, 3 Å

PDB Description: Crystal Structure of the CK2 Tetrameric Holoenzyme

PDB Compounds: (D:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d4dgld_:

Sequence; same for both SEQRES and ATOM records:

>d4dgld_ d.144.1.7 (D:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
gpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitnn
ekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdfk
qlrqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaefy
hpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydql
vriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfld
kllrydhqsrltareamehpyfytvvkd

Timeline for d4dgld_:

• d4dgld_ first appeared in SCOPe 2.04
  
• d4dgld_ appears in SCOPe 2.06
  
• d4dgld_ appears in the current release, SCOPe 2.08