SCOPe 2.08: Domain d2assa1: 2ass A:1002-1059

Lineage for d2assa1 (2ass A:1002-1059)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.42: POZ domain [54694] (1 superfamily)
   core: beta(2)-alpha(2)-beta(2)-alpha(2); 2 layers a/b; mixed sheet: 2143

4. Superfamily d.42.1: POZ domain [54695] (3 families)

5. Family d.42.1.1: BTB/POZ domain [54696] (6 proteins)

6. Protein Cyclin A/CDK2-associated p45, Skp1 [54710] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54711] (9 PDB entries)

8. Domain d2assa1: 2ass A:1002-1059 [238618]
   Other proteins in same PDB: d2assa2, d2assb1, d2assb2, d2assc_
   automated match to d1fs1b2
   complexed with ben, po4
   missing some secondary structures that made up less than one-third of the common domain

Details for d2assa1

PDB Entry: 2ass, 3 Å

PDB Description: crystal structure of the skp1-skp2-cks1 complex

PDB Compounds: (A:) S-phase kinase-associated protein 1A

SCOPe Domain Sequences for d2assa1:

Sequence, based on SEQRES records:

>d2assa1 d.42.1.1 (A:1002-1059) Cyclin A/CDK2-associated p45, Skp1 {Human (Homo sapiens) [TaxId: 9606]}
asiklqssdgeifevdveiakqsvtiktmledlgmddegdddpvplpnvnaailkkviqw
cthh

Sequence, based on observed residues (ATOM records):

>d2assa1 d.42.1.1 (A:1002-1059) Cyclin A/CDK2-associated p45, Skp1 {Human (Homo sapiens) [TaxId: 9606]}
asiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthh

Timeline for d2assa1:

• d2assa1 first appeared in SCOPe 2.04
  
• d2assa1 appears in SCOPe 2.07