SCOPe 2.07: Domain d4h0ua_: 4h0u A:

Lineage for d4h0ua_ (4h0u A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein automated matches [190469] (17 species)
   not a true protein

7. Species Corynebacterium glutamicum [TaxId:196627] [227854] (2 PDB entries)

8. Domain d4h0ua_: 4h0u A: [234590]
   automated match to d4h0ra_
   complexed with ump

Details for d4h0ua_

PDB Entry: 4h0u, 2.75 Å

PDB Description: Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d4h0ua_:

Sequence, based on SEQRES records:

>d4h0ua_ d.117.1.1 (A:) automated matches {Corynebacterium glutamicum [TaxId: 196627]}
mtvptpyedllrkiaeegshkddrtgtgttslfgqqirfdlnegfpllttkkvhfhsvvg
ellwflqgdsnvkwlqdnniriwnewadedgelgpvygvqwrswptpdgrhidqisgale
tlrnnpdsrrnivsawnvselenmalppchllfqlyvadgklscqlyqrsadmflgvpfn
iasyallthmfaqqaglevgefiwtggdchiydnhkeqvaeqlsrearpyptlelnkaas
mfeysfdditvsgydphplirgkv

Sequence, based on observed residues (ATOM records):

>d4h0ua_ d.117.1.1 (A:) automated matches {Corynebacterium glutamicum [TaxId: 196627]}
mtvptpyedllrkiaeegshkdtgttslfgqqirfdlnegfpllttkkvhfhsvvgellw
flqgdsnvkwlqdnniriwnewadedgelgpvygvqwrswptpdgrhidqisgaletlrn
npdsrrnivsawnvselenmalppchllfqlyvadgklscqlyqrsadmflgvpfniasy
allthmfaqqaglevgefiwtggdchiydnhkeqvaeqlsrearpyptlelnkaasmfey
sfdditvsgydphplirgkv

Timeline for d4h0ua_:

• d4h0ua_ first appeared in SCOPe 2.03
  
• d4h0ua_ appears in SCOPe 2.06
  
• d4h0ua_ appears in the current release, SCOPe 2.08