SCOPe 2.04: Domain d3wiya_: 3wiy A:

Lineage for d3wiya_ (3wiy A:)

1. Root: SCOPe 2.04

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (34 PDB entries)

8. Domain d3wiya_: 3wiy A: [233967]
   automated match to d3wiye_
   complexed with lc6

Details for d3wiya_

PDB Entry: 3wiy, 2.15 Å

PDB Description: Crystal structure of Mcl-1 in complex with compound 10

PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d3wiya_:

Sequence; same for both SEQRES and ATOM records:

>d3wiya_ f.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhved

Timeline for d3wiya_:

• d3wiya_ first appeared in SCOPe 2.03
  
• d3wiya_ appears in SCOPe 2.05
  
• d3wiya_ appears in the current release, SCOPe 2.08