SCOPe 2.07: Domain d3i3ra2: 3i3r A:205-510

Lineage for d3i3ra2 (3i3r A:205-510)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.0: automated matches [227244] (1 protein)
   not a true family

6. Protein automated matches [227010] (5 species)
   not a true protein

7. Species Babesia bovis [TaxId:484906] [232544] (3 PDB entries)

8. Domain d3i3ra2: 3i3r A:205-510 [232545]
   Other proteins in same PDB: d3i3ra1, d3i3rb1
   automated match to d1qzfa2
   complexed with cl

Details for d3i3ra2

PDB Entry: 3i3r, 2.35 Å

PDB Description: x-ray structure dihydrofolate reductase/thymidylate synthase from babesia bovis at 2.35a resolution

PDB Compounds: (A:) Dihydrofolate reductase/thymidylate synthase

SCOPe Domain Sequences for d3i3ra2:

Sequence, based on SEQRES records:

>d3i3ra2 d.117.1.0 (A:205-510) automated matches {Babesia bovis [TaxId: 484906]}
gtdisvpkpkyvacpgvrirnheefqyldiladvlshgvlkpnrtgtdayskfgyqmrfd
lsrsfpllttkkvalrsiieellwfikgstngndllaknvriwelngrrdfldkngftdr
eehdlgpiygfqwrhfgaeyldmhadytgkgidqlaeiinriktnpndrrlivcswnvsd
lkkmalppchcffqfyvsdnklscmmhqrscdlglgvpfniasysiltamvaqvcglglg
efvhnladahiyvdhvdavttqiariphpfprlrlnpdirniedftiddivvedyvshpp
ipmams

Sequence, based on observed residues (ATOM records):

>d3i3ra2 d.117.1.0 (A:205-510) automated matches {Babesia bovis [TaxId: 484906]}
gtdiskpkyvacpgvrirnheefqyldiladvlshgvlkpnrtgtdayskfgyqmrfdls
rsfpllttkkvalrsiieellwfikgstngndllaknvriwelngrrdfldkngftdree
hdlgpiygfqwrhfgaeyldmhadytgkgidqlaeiinriktnpndrrlivcswnvsdlk
kmalppchcffqfyvsdnklscmmhqrscdlglgvpfniasysiltamvaqvcglglgef
vhnladahiyvdhvdavttqiariphpfprlrlnpdirniedftiddivvedyvshppip
mams

Timeline for d3i3ra2:

• d3i3ra2 first appeared in SCOPe 2.03
  
• d3i3ra2 appears in SCOPe 2.06
  
• d3i3ra2 appears in the current release, SCOPe 2.08