Lineage for d1faih1 (1fai H:9-123)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (181 PDB entries)
    Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E ! SQ NA # humanized antibody ! Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor ! Uniprot P01750 20-116 # ! HV06_MOUSE Ig heavy chain V region 102 precursor
  8. Domain d1faih1: 1fai H:9-123 [19845]
    Other proteins in same PDB: d1faih2, d1faih3, d1fail1, d1fail2
    part of Fab R19.9

Details for d1faih1

PDB Entry: 1fai (more details), 2.7 Å

PDB Description: three-dimensional structure of two crystal forms of fab r19.9, from a monoclonal anti-arsonate antibody
PDB Compounds: (H:) igg2b-kappa r19.9 fab (heavy chain)

SCOPe Domain Sequences for d1faih1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1faih1 b.1.1.1 (H:9-123) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
aelvragssvkmsckasgytftsygvnwvkqrpgqglewigyinpgkgylsynekfkgkt
tltvdrssstaymqlrsltsedaavyfcarsfyggsdlavyyfdswgqgttltvs

SCOPe Domain Coordinates for d1faih1 are not available.

Timeline for d1faih1:

View in 3D
Domains from same chain:
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d1faih2, d1faih3
View in 3D
Domains from other chains:
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d1fail1, d1fail2