SCOPe 2.03: Domain d2aa6b_: 2aa6 B:

Lineage for d2aa6b_ (2aa6 B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (121 PDB entries)

8. Domain d2aa6b_: 2aa6 B: [193194]
   automated match to d3vhva_
   complexed with str; mutant

Details for d2aa6b_

PDB Entry: 2aa6, 1.95 Å

PDB Description: mineralocorticoid receptor s810l mutant with bound progesterone

PDB Compounds: (B:) Mineralocorticoid receptor

SCOPe Domain Sequences for d2aa6b_:

Sequence, based on SEQRES records:

>d2aa6b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alvpqlstisraltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvv
kwakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmh
qsamyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyik
elrkmvtkcpnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlv
eiisdqlpkvesgnakplyfh

Sequence, based on observed residues (ATOM records):

>d2aa6b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alvpqlstisraltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvv
kwakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmh
qsamyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyik
elrkmvtpnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlvei
isdqlpkvesgnakplyfh

Timeline for d2aa6b_:

• d2aa6b_ first appeared in SCOPe 2.02
  
• d2aa6b_ appears in SCOPe 2.04
  
• d2aa6b_ appears in the current release, SCOPe 2.08