SCOPe 2.04: Domain d2zvtb_: 2zvt B:

Lineage for d2zvtb_ (2zvt B:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
7. Species Human (Homo sapiens) [TaxId:9606] [48525] (85 PDB entries)
   Uniprot P37231 232-505

8. Domain d2zvtb_: 2zvt B: [191692]
   automated match to d3ty0a_
   protein/DNA complex; complexed with ptg; mutant

Details for d2zvtb_

PDB Entry: 2zvt, 1.9 Å

PDB Description: cys285ser mutant ppargamma ligand-binding domain complexed with 15- deoxy-delta12,14-prostaglandin j2

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d2zvtb_:

Sequence, based on SEQRES records:

>d2zvtb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgsqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiy

Sequence, based on observed residues (ATOM records):

>d2zvtb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgsqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktethpllqeiy

Timeline for d2zvtb_:

• d2zvtb_ first appeared in SCOPe 2.02
  
• d2zvtb_ appears in SCOPe 2.03
  
• d2zvtb_ appears in SCOPe 2.05
  
• d2zvtb_ appears in the current release, SCOPe 2.08