SCOPe 2.04: Domain d3pbaa_: 3pba A:

Lineage for d3pbaa_ (3pba A:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
7. Species Human (Homo sapiens) [TaxId:9606] [48525] (85 PDB entries)
   Uniprot P37231 232-505

8. Domain d3pbaa_: 3pba A: [183629]
   automated match to d1nyxa_
   complexed with pgo, zxg

Details for d3pbaa_

PDB Entry: 3pba, 2.3 Å

PDB Description: Crystal structure of PPARgamma ligand binding domain in complex with monosulfate tetrabromo-bisphenol A (MonoTBBPA)

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3pbaa_:

Sequence, based on SEQRES records:

>d3pbaa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkik
fkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvh
eiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsd
laifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlr
qivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3pbaa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkis
kevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslm
nkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviils
gdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllq
vikktetdmslhpllqeiykdl

Timeline for d3pbaa_:

• d3pbaa_ first appeared in SCOPe 2.01
  
• d3pbaa_ appears in SCOPe 2.03
  
• d3pbaa_ appears in SCOPe 2.05
  
• d3pbaa_ appears in the current release, SCOPe 2.08