SCOPe 2.03: Domain d3nz0a_: 3nz0 A:

Lineage for d3nz0a_ (3nz0 A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d3nz0a_: 3nz0 A: [182635]
   automated match to d1u46a_
   complexed with iza

Details for d3nz0a_

PDB Entry: 3nz0, 2 Å

PDB Description: Non-phosphorylated TYK2 kinase with CMP6

PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d3nz0a_:

Sequence, based on SEQRES records:

>d3nz0a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadcgpqhrsgwkqe
idilrtlyhehiikykgccedqgekslqlvmeyvplgslrdylprhsiglaqlllfaqqi
cegmaylhaqhyihrnlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligiaqgqmtvlrltel
lergerlprpdkcpcevyhlmkncweteasfrptfenlipilktvhekyrh

Sequence, based on observed residues (ATOM records):

>d3nz0a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadcgpqhrsgwkqe
idilrtlyhehiikykgccedqgekslqlvmeyvplgslrdylprhsiglaqlllfaqqi
cegmaylhaqhyihrnlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligtvlrltellerger
lprpdkcpcevyhlmkncweteasfrptfenlipilktvhekyrh

Timeline for d3nz0a_:

• d3nz0a_ first appeared in SCOPe 2.01
  
• d3nz0a_ appears in SCOPe 2.02
  
• d3nz0a_ appears in SCOPe 2.04
  
• d3nz0a_ appears in the current release, SCOPe 2.08, called d3nz0a1