SCOPe 2.08: Domain d3klae1: 3kla E:1-99

Lineage for d3klae1 (3kla E:1-99)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (480 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d3klae1: 3kla E:1-99 [179426]
   Other proteins in same PDB: d3klab2, d3klae2
   automated match to d1a9bb_

Details for d3klae1

PDB Entry: 3kla, 1.65 Å

PDB Description: ca2+ release from the endoplasmic reticulum of ny-eso-1 specific t cells is modulated by the affinity of t cell receptor and by the use of the cd8 co-receptor

PDB Compounds: (E:) Beta-2-microglobulin

SCOPe Domain Sequences for d3klae1:

Sequence; same for both SEQRES and ATOM records:

>d3klae1 b.1.1.2 (E:1-99) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d3klae1:

• d3klae1 first appeared in SCOPe 2.01, called d3klae_
  
• d3klae1 appears in SCOPe 2.07