SCOPe 2.07: Domain d2wxvc1: 2wxv C:1-298

Lineage for d2wxvc1 (2wxv C:1-298)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (892 PDB entries)

8. Domain d2wxvc1: 2wxv C:1-298 [169685]
   Other proteins in same PDB: d2wxva2, d2wxvb1, d2wxvb2, d2wxvc2, d2wxvd1, d2wxvd2
   automated match to d1vywa_
   complexed with so4, wxv

Details for d2wxvc1

PDB Entry: 2wxv, 2.6 Å

PDB Description: structure of cdk2-cyclin a with a pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor

PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wxvc1:

Sequence; same for both SEQRES and ATOM records:

>d2wxvc1 d.144.1.7 (C:1-298) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d2wxvc1:

• d2wxvc1 first appeared in SCOPe 2.01, called d2wxvc_
  
• d2wxvc1 appears in SCOPe 2.06
  
• d2wxvc1 appears in the current release, SCOPe 2.08