SCOPe 2.03: Domain d2r24a_: 2r24 A:

Lineage for d2r24a_ (2r24 A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein automated matches [190169] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188399] (51 PDB entries)

8. Domain d2r24a_: 2r24 A: [167929]
   automated match to d1el3a_
   complexed with ldt, nap

Details for d2r24a_

PDB Entry: 2r24, 1.75 Å

PDB Description: human aldose reductase structure

PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d2r24a_:

Sequence; same for both SEQRES and ATOM records:

>d2r24a_ c.1.7.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
masrlllnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef

Timeline for d2r24a_:

• d2r24a_ first appeared in SCOPe 2.01
  
• d2r24a_ appears in SCOPe 2.02
  
• d2r24a_ appears in SCOPe 2.04
  
• d2r24a_ appears in the current release, SCOPe 2.08