SCOPe 2.08: Domain d2b1vb_: 2b1v B:

Lineage for d2b1vb_ (2b1v B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d2b1vb_: 2b1v B: [162968]
   automated match to d1qkua_
   complexed with 458

Details for d2b1vb_

PDB Entry: 2b1v, 1.8 Å

PDB Description: human estrogen receptor alpha ligand-binding domain in complex with obcp-1m and a glucocorticoid receptor interacting protein 1 nr box ii peptide

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d2b1vb_:

Sequence, based on SEQRES records:

>d2b1vb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahrl

Sequence, based on observed residues (ATOM records):

>d2b1vb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahl

Timeline for d2b1vb_:

• d2b1vb_ first appeared in SCOPe 2.01
  
• d2b1vb_ appears in SCOPe 2.07