SCOPe 2.04: Family d.3.1.22: Autophagin-like

Lineage for Family d.3.1.22: Autophagin-like

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.22: Autophagin-like [159858] (3 proteins)
   Pfam PF03416

Proteins:

1. Cysteine protease ATG4A [159859] (1 species)
   Autophagin-2

   • Species Human (Homo sapiens) [TaxId:9606] [159860] (1 PDB entry)
     Uniprot Q8WYN0 26-359

2. Cysteine protease ATG4B [159861] (1 species)
   Autophagin-1

   • Species Human (Homo sapiens) [TaxId:9606] [159862] (2 PDB entries)
     Uniprot Q9Y4P1 10-373! Uniprot Q9Y4P1 5-354

3. automated matches [190846] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [188165] (3 PDB entries)

More info for Family d.3.1.22: Autophagin-like

Timeline for Family d.3.1.22: Autophagin-like:

• Family d.3.1.22: Autophagin-like first appeared in SCOP 1.75
  
• Family d.3.1.22: Autophagin-like appears in SCOPe 2.03
  
• Family d.3.1.22: Autophagin-like appears in SCOPe 2.05
  
• Family d.3.1.22: Autophagin-like appears in the current release, SCOPe 2.08