SCOPe 2.07: Domain d2quja2: 2quj A:88-471

Lineage for d2quja2 (2quj A:88-471)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 proteins)
   contains a conserved all-alpha subdomain at the C-terminal extension

6. Protein Tryptophanyl-tRNA synthetase (TrpRS) [52378] (5 species)
   overall structure is similar to TyrRS

7. Species Human (Homo sapiens) [TaxId:9606] [102256] (13 PDB entries)
   Uniprot P23381 94-471

8. Domain d2quja2: 2quj A:88-471 [151373]
   Other proteins in same PDB: d2quja3
   automated match to d1r6ua_
   protein/RNA complex; complexed with cl, gol, trp, tym

Details for d2quja2

PDB Entry: 2quj, 2.42 Å

PDB Description: Crystal structures of human tryptophanyl-tRNA synthetase in complex with TrpAMP

PDB Compounds: (A:) Tryptophanyl-tRNA synthetase

SCOPe Domain Sequences for d2quja2:

Sequence; same for both SEQRES and ATOM records:

>d2quja2 c.26.1.1 (A:88-471) Tryptophanyl-tRNA synthetase (TrpRS) {Human (Homo sapiens) [TaxId: 9606]}
wtvqtssakgidydklivrfgsskidkelinrieratgqrphhflrrgiffshrdmnqvl
dayenkkpfylytgrgpsseamhvghlipfiftkwlqdvfnvplviqmtddekylwkdlt
ldqaysyavenakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgif
gftdsdcigkisfpaiqaapsfsnsfpqifrdrtdiqclipcaidqdpyfrmtrdvapri
gypkpallhstffpalqgaqtkmsasdpnssifltdtakqiktkvnkhafsggrdtieeh
rqfggncdvdvsfmyltffledddkleqirkdytsgamltgelkkalievlqpliaehqa
rrkevtdeivkefmtprklsfdfq

Timeline for d2quja2:

• d2quja2 first appeared in SCOP 1.75, called d2quja1
  
• d2quja2 appears in SCOPe 2.06
  
• d2quja2 appears in the current release, SCOPe 2.08