SCOPe 2.03: Domain d2pjta_: 2pjt A:

Lineage for d2pjta_ (2pjt A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Collagenase-3 (MMP-13) [55540] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55541] (30 PDB entries)

8. Domain d2pjta_: 2pjt A: [149575]
   automated match to d1euba_
   complexed with 347, ca, zn

Details for d2pjta_

PDB Entry: 2pjt, 2.8 Å

PDB Description: Crystal structure of the catalytic domain of MMP-13 complexed with WAY-344

PDB Compounds: (A:) collagenase 3

SCOPe Domain Sequences for d2pjta_:

Sequence, based on SEQRES records:

>d2pjta_ d.92.1.11 (A:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp

Sequence, based on observed residues (ATOM records):

>d2pjta_ d.92.1.11 (A:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytythfmlpdddvqgiqslygp

Timeline for d2pjta_:

• d2pjta_ first appeared in SCOP 1.75, called d2pjta1
  
• d2pjta_ appears in SCOPe 2.02
  
• d2pjta_ appears in SCOPe 2.04
  
• d2pjta_ appears in the current release, SCOPe 2.08