SCOPe 2.03: Domain d2onca1: 2onc A:41-508

Lineage for d2onca1 (2onc A:41-508)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.70: 8-bladed beta-propeller [50997] (3 superfamilies)
   consists of eight 4-stranded beta-sheet motifs; meander
   also found in some members of the WD40-repeat superfamily

4. Superfamily b.70.3: DPP6 N-terminal domain-like [82171] (1 family)
   automatically mapped to Pfam PF00930

5. Family b.70.3.1: DPP6 N-terminal domain-like [82172] (3 proteins)
   Pfam PF00930

6. Protein Dipeptidyl peptidase IV/CD26, N-terminal domain [82173] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82174] (68 PDB entries)
   Uniprot P27487 39-776 ! Uniprot P27487 ! Uniprot P27487

8. Domain d2onca1: 2onc A:41-508 [148891]
   Other proteins in same PDB: d2onca2, d2oncb2, d2oncc2, d2oncd2
   automatically matched to d1orva1
   complexed with nag, sy1

Details for d2onca1

PDB Entry: 2onc, 2.55 Å

PDB Description: crystal structure of human dpp-4

PDB Compounds: (A:) dipeptidyl peptidase 4

SCOPe Domain Sequences for d2onca1:

Sequence, based on SEQRES records:

>d2onca1 b.70.3.1 (A:41-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
ktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdefgh
sindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwspv
ghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspng
tflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssvt
natsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwncl
varqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitkg
twevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysvs
fskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Sequence, based on observed residues (ATOM records):

>d2onca1 b.70.3.1 (A:41-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
ktytltdylkntyrlklyslrwisdheylyknilvfnaeygnssvflenstfdefghsin
dysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwspvghk
layvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspngtfl
ayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssvtnat
siqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwnclvar
qhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitkgtwe
vigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysvsfsk
eakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Timeline for d2onca1:

• d2onca1 first appeared in SCOP 1.75
  
• d2onca1 appears in SCOPe 2.02
  
• d2onca1 appears in SCOPe 2.04
  
• d2onca1 appears in the current release, SCOPe 2.08