SCOPe 2.08: Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins

Lineage for Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.58: Ferredoxin-like [54861] (62 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins [117987] (8 families)

Families:

1. d.58.53.1: CRISPR-associated endoribonuclease Cse3-like [117988] (2 proteins)
   duplication: contains two subdomains of this fold

2. d.58.53.2: CRISPR-associated protein Cas5d-like [345973] (2 proteins)
   Pfam PF09704. Contains several beta-sheet insertions to the common fold

3. d.58.53.3: CRISPR-associated protein Cas6-like [418820] (1 protein)
   Pfam PF01881; duplication

4. d.58.53.4: CRISPR-associated protein Cas7/Csa2-like [418821] (1 protein)
   Pfam PF01905; likely homology with Cas6 described in PubMed 21507944
   contains multiple insertions into the common RRM-like fold: N- and C-terminal helical subdomains, and a lid-like domain

5. d.58.53.5: CRISPR-associated protein Csm3-like [418822] (1 protein)
   Pfam PF03787; homology with Csa2 described in PubMed 24157656
   contains multiple insertions into the common RRM-like fold, similar to Csa2 (d.58.53.3)

6. d.58.53.6: CRISPR-associated protein Csy4-like [418841] (2 proteins)
   Pfam PF09618; duplication, but second domain has a different fold due to interaction with RNA, described in PubMed 20829488

7. d.58.53.7: Nucleotide cyclase domains from Cmr2-like [418857] (3 proteins)
   Pfam PF12469
   duplication; first domain contains additional zinc finger subdomain described in PubMed 22405013

8. d.58.53.0: automated matches [231597] (1 protein)
   not a true family

More info for Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins

Timeline for Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins:

• Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins first appeared in SCOP 1.71, called Superfamily d.58.53: CRISPR-associated protein
  
• Superfamily d.58.53: Ferredoxin-like domains from CRISPR-associated proteins appears in SCOPe 2.07