SCOP 1.71: Domain d1rs0a1: 1rs0 A:453-739

Lineage for d1rs0a1 (1rs0 A:453-739)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Factor B [50561] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50562] (4 PDB entries)

8. Domain d1rs0a1: 1rs0 A:453-739 [111930]
   Other proteins in same PDB: d1rs0a2
   complexed with dfp, iod, mg, na; mutant

Details for d1rs0a1

PDB Entry: 1rs0, 2.6 Å

PDB Description: crystal structure analysis of the bb segment of factor b complexed with di-isopropyl-phosphate (dip)

SCOP Domain Sequences for d1rs0a1:

Sequence, based on SEQRES records:

>d1rs0a1 b.47.1.2 (A:453-739) Factor B {Human (Homo sapiens)}
cgmvwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsi
kvsvggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpicl
pctegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgsce
rdaqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgvi
swgvvdvcknqkrqkqvpahardfhinlfqvlpwlkeklqdedlgfl

Sequence, based on observed residues (ATOM records):

>d1rs0a1 b.47.1.2 (A:453-739) Factor B {Human (Homo sapiens)}
cgmvwehrkgtdyhkqpwqakisvirkghescmgavvseyfvltaahcftvddkehsikv
svggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpiclpc
tegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgscerd
aqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgvisw
gvvdvcvpahardfhinlfqvlpwlkeklqdedlgfl

Timeline for d1rs0a1:

• d1rs0a1 is new in SCOP 1.71
  
• d1rs0a1 appears in SCOP 1.73
  
• d1rs0a1 appears in the current release, SCOPe 2.08