PDB entry 7oal

View 7oal on RCSB PDB site
Description: Crystal structure of pseudokinase CASK in complex with compound 25
Class: transferase
Keywords: pseudokinase, kinase, inhibitor, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2021-04-19, released 2021-05-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-05-19, with a file datestamp of 2021-05-14.
Experiment type: XRAY
Resolution: 2.17 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peripheral plasma membrane protein CASK
    Species: Homo sapiens [TaxId:9606]
    Gene: CASK, LIN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7oala_
  • Chain 'B':
    Compound: Peripheral plasma membrane protein CASK
    Species: Homo sapiens [TaxId:9606]
    Gene: CASK, LIN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7oalb_
  • Chain 'C':
    Compound: Peripheral plasma membrane protein CASK
    Species: Homo sapiens [TaxId:9606]
    Gene: CASK, LIN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7oalc_
  • Chain 'D':
    Compound: Peripheral plasma membrane protein CASK
    Species: Homo sapiens [TaxId:9606]
    Gene: CASK, LIN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7oald_
  • Heterogens: V62, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7oalA (A:)
smgspgisgggggirtmadddvlfedvyelcevigkgpfsvvrrcinretgqqfavkivd
vakftsspglstedlkreasichmlkhphivelletyssdgmlymvfefmdgadlcfeiv
kradagfvyseavashymrqilealrychdnniihrdvkphcvllaskensapvklggfg
vaiqlgesglvaggrvgtphfmapevvkrepygkpvdvwgcgvilfillsgclpfygtke
rlfegiikgkykmnprqwshisesakdlvrrmlmldpaeritvyealnhpwlkerdryay
kihlpetveqlrkfnarrklkgavlaavsshkfnsfygdppeelpdfsedpts

    Sequence, based on observed residues (ATOM records): (download) 
    >7oalA (A:)
vlfedvyelcevigkgpfsvvrrcinretgqqfavkivdvakftsspglstedlkreasi
chmlkhphivelletyssdgmlymvfefmdgadlcfeivkradagfvyseavashymrqi
lealrychdnniihrdvkphcvllaskensapvklggfgvaiqlgesglvaggrvgtphf
mapevvkrepygkpvdvwgcgvilfillsgclpfygtkerlfegiikgkykmnprqwshi
sesakdlvrrmlmldpaeritvyealnhpwlkerdryaykihlpetveqlrkfnarrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7oalB (B:)
smgspgisgggggirtmadddvlfedvyelcevigkgpfsvvrrcinretgqqfavkivd
vakftsspglstedlkreasichmlkhphivelletyssdgmlymvfefmdgadlcfeiv
kradagfvyseavashymrqilealrychdnniihrdvkphcvllaskensapvklggfg
vaiqlgesglvaggrvgtphfmapevvkrepygkpvdvwgcgvilfillsgclpfygtke
rlfegiikgkykmnprqwshisesakdlvrrmlmldpaeritvyealnhpwlkerdryay
kihlpetveqlrkfnarrklkgavlaavsshkfnsfygdppeelpdfsedpts

    Sequence, based on observed residues (ATOM records): (download) 
    >7oalB (B:)
vlfedvyelcevigkgpfsvvrrcinretgqqfavkivdvakftsspglstedlkreasi
chmlkhphivelletyssdgmlymvfefmdgadlcfeivkradagfvyseavashymrqi
lealrychdnniihrdvkphcvllaskensapvklggfgvaiqlgesglvaggrvgtphf
mapevvkrepygkpvdvwgcgvilfillsgclpfygtkerlfegiikgkykmnprqwshi
sesakdlvrrmlmldpaeritvyealnhpwlkerdryaykihlpetveqlrkfnarrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7oalC (C:)
smgspgisgggggirtmadddvlfedvyelcevigkgpfsvvrrcinretgqqfavkivd
vakftsspglstedlkreasichmlkhphivelletyssdgmlymvfefmdgadlcfeiv
kradagfvyseavashymrqilealrychdnniihrdvkphcvllaskensapvklggfg
vaiqlgesglvaggrvgtphfmapevvkrepygkpvdvwgcgvilfillsgclpfygtke
rlfegiikgkykmnprqwshisesakdlvrrmlmldpaeritvyealnhpwlkerdryay
kihlpetveqlrkfnarrklkgavlaavsshkfnsfygdppeelpdfsedpts

    Sequence, based on observed residues (ATOM records): (download) 
    >7oalC (C:)
vlfedvyelcevigkgpfsvvrrcinretgqqfavkivdvakftsspglstedlkreasi
chmlkhphivelletyssdgmlymvfefmdgadlcfeivkradagfvyseavashymrqi
lealrychdnniihrdvkphcvllaskensapvklggfgvaiqlgesglvaggrvgtphf
mapevvkrepygkpvdvwgcgvilfillsgclpfygtkerlfegiikgkykmnprqwshi
sesakdlvrrmlmldpaeritvyealnhpwlkerdryaykihlpetveqlrkfnarrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7oalD (D:)
smgspgisgggggirtmadddvlfedvyelcevigkgpfsvvrrcinretgqqfavkivd
vakftsspglstedlkreasichmlkhphivelletyssdgmlymvfefmdgadlcfeiv
kradagfvyseavashymrqilealrychdnniihrdvkphcvllaskensapvklggfg
vaiqlgesglvaggrvgtphfmapevvkrepygkpvdvwgcgvilfillsgclpfygtke
rlfegiikgkykmnprqwshisesakdlvrrmlmldpaeritvyealnhpwlkerdryay
kihlpetveqlrkfnarrklkgavlaavsshkfnsfygdppeelpdfsedpts

    Sequence, based on observed residues (ATOM records): (download) 
    >7oalD (D:)
vlfedvyelcevigkgpfsvvrrcinretgqqfavkivdvakftsspglstedlkreasi
chmlkhphivelletyssdgmlymvfefmdgadlcfeivkradagfvyseavashymrqi
lealrychdnniihrdvkphcvllaskensapvklggfgvaiqlgesglvaggrvgtphf
mapevvkrepygkpvdvwgcgvilfillsgclpfygtkerlfegiikgkykmnprqwshi
sesakdlvrrmlmldpaeritvyealnhpwlkerdryaykihlpetveqlrkfnarrk