PDB entry 7nos

View 7nos on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis ArgF in complex with 4-bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole.
Class: transferase
Keywords: ArgF, Ornithine Carbamoyltransferase, TRANSFERASE
Deposited on 2021-02-25, released 2021-06-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d7nosa1, d7nosa2, d7nosa3
  • Chain 'B':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.07: d7nosb1, d7nosb2, d7nosb3
  • Chain 'C':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.07: d7nosc1, d7nosc2, d7nosc3
  • Chain 'D':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.07: d7nosd1, d7nosd2, d7nosd3
  • Chain 'E':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.07: d7nose1, d7nose2, d7nose3
  • Chain 'F':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d7nosf1, d7nosf2, d7nosf3
  • Heterogens: UJZ, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7nosA (A:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7nosA (A:)
svirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfel
giaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpv
inalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtva
apegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldrv
kpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkal
lvwllers

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7nosB (B:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7nosB (B:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtvkpfrpfqlnsrl
laladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7nosC (C:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7nosC (C:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldrvk
pfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkall
vwllers

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7nosD (D:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7nosD (D:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtldrvkpfrpfqln
srllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7nosE (E:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7nosE (E:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsglgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvinal
sdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaapeg
flpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtgldrvkpfrpfqlnsr
llaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7nosF (F:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7nosF (F:)
svirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfel
giaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpv
inalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtva
apegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtldrvkpfrpfql
nsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers