PDB entry 7kcx

View 7kcx on RCSB PDB site
Description: Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) mutant (R200L) in complex with cefoxitin
Class: hydrolase/hydrolase inhibitor
Keywords: acyl-enzyme intermediate, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2020-10-07, released 2021-06-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Penicillin-binding protein 4
    Species: Staphylococcus aureus (strain COL) [TaxId:93062]
    Gene: pbp4, SACOL0699
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0H2WY27 (Start-366)
      • engineered mutation (183)
    Domains in SCOPe 2.07: d7kcxa1, d7kcxa2
  • Heterogens: 1S7, GOL, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kcxA (A:)
gshmyaqatnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasm
tklmtmyltleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitv
snssnaaalilakkvskntsdfvdlmnnkakaigmknthfvnptgaensrlrtfaptkyk
dqeltvttardyaildlhviketpkildftkqlaptthavtyytfnfslegakmslpgtd
glktgssdtanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqyk
yvkilskgeqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygp
ptvevhq

    Sequence, based on observed residues (ATOM records): (download) 
    >7kcxA (A:)
qatnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtm
yltleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssna
aalilakkvskntsdfvdlmnnkakaigmknthfvnptgaensrlrtfaptkykdqeltv
ttardyaildlhviketpkildftkqlaptthavtyytfnfslegakmslpgtdglktgs
sdtanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqykyvkils
kgeqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevh
q