PDB entry 7c3s

View 7c3s on RCSB PDB site
Description: Crystal structure of NE0047 (E143D) mutant in complex with 8-azaguanine
Class: hydrolase
Keywords: hydrolase, deaminase, 8-azaguanine, complex
Deposited on 2020-05-14, released 2021-05-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytidine and deoxycytidylate deaminase zinc-binding region
    Species: Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) [TaxId:228410]
    Gene: NE0047
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q82Y41
      • engineered mutation (144)
    Domains in SCOPe 2.07: d7c3sa_
  • Chain 'B':
    Compound: Cytidine and deoxycytidylate deaminase zinc-binding region
    Species: Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) [TaxId:228410]
    Gene: NE0047
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q82Y41 (2-End)
      • expression tag (1)
      • engineered mutation (144)
    Domains in SCOPe 2.07: d7c3sb1, d7c3sb2
  • Heterogens: AZG, ZN, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7c3sA (A:)
ghmndalhiglppflvqanneprvlaapearmgyvlelvraniaadggpfaaavferdsg
lliaagtnrvvpgrcsaahaeilalslaqakldthdlsadglpacelvtsaepcvmcfga
viwsgvrslvcaarsddveaigfddgprpenwmggleargitvttgllrdaacallreyn
acngviynarcgvhk

    Sequence, based on observed residues (ATOM records): (download) 
    >7c3sA (A:)
ndalhiglppflvqanneprvlaapearmgyvlelvraniaadggpfaaavferdsglli
aagtnrvvpgrcsaahaeilalslaqakldthdlsadglpacelvtsaepcvmcfgaviw
sgvrslvcaarsddveaigfddgprpenwmggleargitvttgllrdaacallreynacn
gviynarc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7c3sB (B:)
ghmndalhiglppflvqanneprvlaapearmgyvlelvraniaadggpfaaavferdsg
lliaagtnrvvpgrcsaahaeilalslaqakldthdlsadglpacelvtsaepcvmcfga
viwsgvrslvcaarsddveaigfddgprpenwmggleargitvttgllrdaacallreyn
acngviynarcgvhk

    Sequence, based on observed residues (ATOM records): (download) 
    >7c3sB (B:)
hmndalhiglppflvqanneprvlaapearmgyvlelvraniaadggpfaaavferdsgl
liaagtnrvvpgrcsaahaeilalslaqakldthdlsadglpacelvtsaepcvmcfgav
iwsgvrslvcaarsddveaigfddgprpenwmggleargitvttgllrdaacallreyna
cn