PDB entry 7ahv

View 7ahv on RCSB PDB site
Description: Anti-FIXa Fab of mim8 in complex with human FIXa
Class: blood clotting
Keywords: Fab, anti-FIXa, hydrolase, mim8, BLOOD CLOTTING
Deposited on 2020-09-25, released 2021-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 3.11 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: anti-FIXa Fab of mim8 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7AHV (0-223)
    Domains in SCOPe 2.08: d7ahva_
  • Chain 'B':
    Compound: anti-FIXa Fab of mim8 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7AHV (0-213)
    Domains in SCOPe 2.08: d7ahvb_
  • Chain 'H':
    Compound: coagulation factor ix
    Species: Homo sapiens [TaxId:9606]
    Gene: F9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7ahvh_
  • Chain 'L':
    Compound: coagulation factor ix
    Species: Homo sapiens [TaxId:9606]
    Gene: F9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00740 (1-58)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d7ahvl_
  • Heterogens: SO4, 0GJ, CA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7ahvA (A:)
evqlvesggglvqpgrslrlscaasgftfhdyamhwvrqvpgkglewvsgiswrgdiggy
vksvkgrftisrdnaknslylqmnslraedtalyycvksygsgsfynafdswgqgtlvtv
ssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrvesky

    Sequence, based on observed residues (ATOM records): (download) 
    >7ahvA (A:)
evqlvesggglvqpgrslrlscaasgftfhdyamhwvrqvpgkglewvsgiswrgdiggy
vksvkgrftisrdnaknslylqmnslraedtalyycvksygsgsfynafdswgqgtlvtv
ssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrvesk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7ahvB (B:)
diqmtqspstlsasvgdrvtitcrasqsisswlawyqqkpgkapkfliykasklergtps
rfsgsgdgtefsltisslqpddfatyycleyssyirtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdaalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7ahvH (H:)
vvggedakpgqfpwqvvlngkvdafcggsivnekwivtaahcvetgvkitvvagehniee
tehteqkrnviriiphhnynaainkynhdialleldeplvlnsyvtpiciadkeytnifl
kfgsgyvsgwgrvfhkgrsalvlqylrvplvdratclrstkftiynnmfcagfheggrds
cqgdsggphvtevegtsfltgiiswgeecamkgkygiytkvsryvnwikektklt

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7ahvL (L:)
mdvtcnikngrceqfcknsadnkvvcsctegyrlaenqkscepavpfpcgrvsvsqtsk

    Sequence, based on observed residues (ATOM records): (download) 
    >7ahvL (L:)
dvtcnikngrceqfcknsadnkvvcsctegyrlaenqkscepavpfpcgrvsvs