PDB entry 7a4x

View 7a4x on RCSB PDB site
Description: tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant in complex with dimethyl sulfoxide
Class: transferase
Keywords: enzyme, disulfide, fragment, TRANSFERASE
Deposited on 2020-08-20, released 2021-06-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720 (Start-387)
      • engineered mutation (159)
      • engineered mutation (282)
      • engineered mutation (313)
      • engineered mutation (331)
      • engineered mutation (334)
    Domains in SCOPe 2.07: d7a4xa_
  • Heterogens: DMS, ZN, GOL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7a4xA (A:)
gsmveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpet
vratgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqs
eegvtfkshldgsrhmlspersieiqhllgsdivmafdestpypatpsraassmersmrw
akrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqd
emfrvldfsvpmlpddkphylmgvgkpddivgavergidmfdsvlptrsgrngqaftwdg
pinirnarfsedlkpldsechcavcqkwsracihalirageilgamlmtehniafyqqlm
qkirdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >7a4xA (A:)
tdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiil
gntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslsltkqseegvtfkshld
gsrhmlspersieiqhllgsdivmafdestpypatpsraassmersmrwakrsrdafdsr
keqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvp
mlpddkphylmgvgkpddivgavergidmfdsvlptrsgrngqaftwdgpinirnarfse
dlkpldsechcavcqkwsracihalirageilgamlmtehniafyqqlmqkirdsisegr
fsqfaqdfraryfarns