PDB entry 6xgs

View 6xgs on RCSB PDB site
Description: Crystal Structure of Dihydrodipicolinate synthase (DHDPS) from Brucella suis 1330
Class: biosynthetic protein, lyase
Keywords: SSGCID, 4-hydroxy-tetrahydrodipicolinate synthase, Dihydrodipicolinate synthase, Brucella suis, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, BIOSYNTHETIC PROTEIN, LYASE
Deposited on 2020-06-18, released 2020-07-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Brucella suis biovar 1 [TaxId:204722]
    Gene: dapA, BR0646, BS1330_I0642
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8G1R0 (21-313)
      • expression tag (20)
    Domains in SCOPe 2.07: d6xgsa1, d6xgsa2
  • Chain 'B':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Brucella suis biovar 1 [TaxId:204722]
    Gene: dapA, BR0646, BS1330_I0642
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8G1R0 (21-313)
      • expression tag (20)
    Domains in SCOPe 2.07: d6xgsb1, d6xgsb2
  • Chain 'C':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Brucella suis biovar 1 [TaxId:204722]
    Gene: dapA, BR0646, BS1330_I0642
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8G1R0 (21-313)
      • expression tag (20)
    Domains in SCOPe 2.07: d6xgsc1, d6xgsc2
  • Chain 'D':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Brucella suis biovar 1 [TaxId:204722]
    Gene: dapA, BR0646, BS1330_I0642
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8G1R0 (21-313)
      • expression tag (20)
    Domains in SCOPe 2.07: d6xgsd1, d6xgsd2
  • Heterogens: CIT, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xgsA (A:)
mahhhhhhmgtleaqtqgpgsmlkgsitalvtpfdregafdekafrafvnwqieegtkgl
vpvgttgetptlshdehkrvievcievaagrvpviagagsnntveaielaqhaekagada
vlvvtpyynkpnqrglyehfsrvvrsisiplviynipgrsiidmtpetmgalvrdckniv
gvkdatgkiervseqraicgkefiqlsgedatalgfnahggvgcisvtsniaprlcaefq
eacqagnfakalelqdrlmplhkalflepnpsgpkyalsrlgrienvlrspmvtieaata
ekidhamkhaglin

    Sequence, based on observed residues (ATOM records): (download) 
    >6xgsA (A:)
smlkgsitalvtpfdregafdekafrafvnwqieegtkglvpvgttgetptlshdehkrv
ievcievaagrvpviagagsnntveaielaqhaekagadavlvvtpyynkpnqrglyehf
srvvrsisiplviynipgrsiidmtpetmgalvrdcknivgvkdatgkiervseqraicg
kefiqlsgedatalgfnahggvgcisvtsniaprlcaefqeacqagnfakalelqdrlmp
lhkalflepnpsgpkyalsrlgrienvlrspmvtieaataekidhamkhaglin

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xgsB (B:)
mahhhhhhmgtleaqtqgpgsmlkgsitalvtpfdregafdekafrafvnwqieegtkgl
vpvgttgetptlshdehkrvievcievaagrvpviagagsnntveaielaqhaekagada
vlvvtpyynkpnqrglyehfsrvvrsisiplviynipgrsiidmtpetmgalvrdckniv
gvkdatgkiervseqraicgkefiqlsgedatalgfnahggvgcisvtsniaprlcaefq
eacqagnfakalelqdrlmplhkalflepnpsgpkyalsrlgrienvlrspmvtieaata
ekidhamkhaglin

    Sequence, based on observed residues (ATOM records): (download) 
    >6xgsB (B:)
smlkgsitalvtpfdregafdekafrafvnwqieegtkglvpvgttgetptlshdehkrv
ievcievaagrvpviagagsnntveaielaqhaekagadavlvvtpyynkpnqrglyehf
srvvrsisiplviynipgrsiidmtpetmgalvrdcknivgvkdatgkiervseqraicg
kefiqlsgedatalgfnahggvgcisvtsniaprlcaefqeacqagnfakalelqdrlmp
lhkalflepnpsgpkyalsrlgrienvlrspmvtieaataekidhamkhaglin

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6xgsC (C:)
mahhhhhhmgtleaqtqgpgsmlkgsitalvtpfdregafdekafrafvnwqieegtkgl
vpvgttgetptlshdehkrvievcievaagrvpviagagsnntveaielaqhaekagada
vlvvtpyynkpnqrglyehfsrvvrsisiplviynipgrsiidmtpetmgalvrdckniv
gvkdatgkiervseqraicgkefiqlsgedatalgfnahggvgcisvtsniaprlcaefq
eacqagnfakalelqdrlmplhkalflepnpsgpkyalsrlgrienvlrspmvtieaata
ekidhamkhaglin

    Sequence, based on observed residues (ATOM records): (download) 
    >6xgsC (C:)
smlkgsitalvtpfdregafdekafrafvnwqieegtkglvpvgttgetptlshdehkrv
ievcievaagrvpviagagsnntveaielaqhaekagadavlvvtpyynkpnqrglyehf
srvvrsisiplviynipgrsiidmtpetmgalvrdcknivgvkdatgkiervseqraicg
kefiqlsgedatalgfnahggvgcisvtsniaprlcaefqeacqagnfakalelqdrlmp
lhkalflepnpsgpkyalsrlgrienvlrspmvtieaataekidhamkhaglin

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6xgsD (D:)
mahhhhhhmgtleaqtqgpgsmlkgsitalvtpfdregafdekafrafvnwqieegtkgl
vpvgttgetptlshdehkrvievcievaagrvpviagagsnntveaielaqhaekagada
vlvvtpyynkpnqrglyehfsrvvrsisiplviynipgrsiidmtpetmgalvrdckniv
gvkdatgkiervseqraicgkefiqlsgedatalgfnahggvgcisvtsniaprlcaefq
eacqagnfakalelqdrlmplhkalflepnpsgpkyalsrlgrienvlrspmvtieaata
ekidhamkhaglin

    Sequence, based on observed residues (ATOM records): (download) 
    >6xgsD (D:)
smlkgsitalvtpfdregafdekafrafvnwqieegtkglvpvgttgetptlshdehkrv
ievcievaagrvpviagagsnntveaielaqhaekagadavlvvtpyynkpnqrglyehf
srvvrsisiplviynipgrsiidmtpetmgalvrdcknivgvkdatgkiervseqraicg
kefiqlsgedatalgfnahggvgcisvtsniaprlcaefqeacqagnfakalelqdrlmp
lhkalflepnpsgpkyalsrlgrienvlrspmvtieaataekidhamkhaglin