PDB entry 6xdh

View 6xdh on RCSB PDB site
Description: Crystal Structure of NendoU (Uridylate-specific endoribonuclease, nsp15) from Betacoronavirus SARS-CoV-2
Class: Hydrolase/VIRAL PROTEIN
Keywords: SSGCID, endoribonuclease, nsp15, COVID-19, SARS-CoV-2, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, VIRAL PROTEIN, Hydrolase-VIRAL PROTEIN complex
Deposited on 2020-06-10, released 2020-06-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-06-17, with a file datestamp of 2020-06-12.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (22-End)
      • expression tag (20-21)
    Domains in SCOPe 2.07: d6xdha1, d6xdha2, d6xdha3
  • Chain 'B':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (22-367)
      • expression tag (19-21)
    Domains in SCOPe 2.07: d6xdhb1, d6xdhb2, d6xdhb3
  • Heterogens: ACT, CIT, FMT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xdhA (A:)
mgsshhhhhhssgenlyfqghmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgv
dvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahist
igvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpk
qaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelam
defieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvkny
fitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdghv
etfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >6xdhA (A:)
hmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xdhB (B:)
mgsshhhhhhssgenlyfqghmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgv
dvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahist
igvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpk
qaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelam
defieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvkny
fitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdghv
etfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >6xdhB (B:)
ghmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafel
wakrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkptetica
pltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfn
yykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivy
gdfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidl
llddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq