PDB entry 6x5j
View 6x5j on RCSB PDB site
Description: Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors
Class: blood clotting
Keywords: serine protease, zymogen, hydrolase, glycoprotein, hydroxylation, phosphoprotein, sulfation, hemostasis, hemophilia, xase-like variant, communication channel, gamma-carboxyglutamic acid, egf-like domain, disease mutation, blood clotting
Deposited on
2020-05-26, released
2020-06-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-06-24, with a file datestamp of
2020-06-19.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: N/A
AEROSPACI score: 0.21
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: coagulation factor ix
Species: Homo sapiens [TaxId:9606]
Gene: F9
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6x5ja_ - Chain 'B':
Compound: coagulation factor ix
Species: Homo sapiens [TaxId:9606]
Gene: F9
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6x5jb_ - Heterogens: 6NH, GOL, NA, CIT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6x5jA (A:)
vvggedakpgqfpwqvvlngkvdafcggsivnekwivtaahcvetgvkitvvagehniee
tehteqkrnviriiphhnynaainkynhdialleldeplvlnsyvtpiciadkeytnifl
kfgsgyvsgwgrvfhkgrsalvlqylrvplvdratclrstkftiynnmfcagfheggrds
cqgdsggphvtevegtsfltgiiswgeecamkgkygiytkvsryvnwikektklt
Sequence, based on observed residues (ATOM records): (download)
>6x5jA (A:)
vvggedakpgqfpwqvvlngkvdafcggsivnekwivtaahcvetgvkitvvagehniee
tehteqkrnviriiphhnynaainkynhdialleldeplvlnsyvtpiciadkeytnifl
kfgsgyvsgwgrvfhkgrsalvlqylrvplvdratclrstkftiynnmfcagfheggrds
cqgdsggphvtevegtsfltgiiswgeecamkgkygiytkvsryvnwikektkl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6x5jB (B:)
mdvtcnikngrceqfcknsadnkvvcsctegyrlaenqkscepavpfpcgrvsvsqtskl
tr
Sequence, based on observed residues (ATOM records): (download)
>6x5jB (B:)
dvtcnikngrceqfcknvvcsctegyrlaenqkscepavpfpcgrvsvsq