PDB entry 6ubw

View 6ubw on RCSB PDB site
Description: MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody
Class: transferase-transferase inhibitor
Keywords: MET, Tyrosine Kinase, Inhibitor, Antitumor, TRANSFERASE-TRANSFERASE INHIBITOR complex, TRANSFERASE-TRANSFERASE INHIBITOR
Deposited on 2019-09-13, released 2020-02-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ubwa_
  • Heterogens: 84S, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ubwA (A:)
gamgsqvqypltdmspiltsgdsdisspllqntvhidlsalnpelvqavqhvvigpssli
vhfnevigrghfgcvyhgtlldndgkkihcavkslnritdigevsqfltegiimkdfshp
nvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdligfglqvakgmkylas
kkfvhrdlaarncmldekftvkvadfglardmydkeyysvhnktgaklpvkwmaleslqt
qkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevml
kcwhpkaemrpsfselvsrisaifstfigehyvhvnatyvnvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6ubwA (A:)
tdmspinpelvqavqhvvigpsslivhfnevigrghfgcvyhgtllgkkihcavkslnig
evsqfltegiimkdfshpnvlsllgiclplvvlpymkhgdlrnfirnethnptvkdligf
glqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyysvhnktgak
lpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllq
peycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyvhvnatyvnvk