PDB entry 6u4o

View 6u4o on RCSB PDB site
Description: Crystal structure of recombinant class II fumarase from Schistosoma mansoni
Class: lyase
Keywords: SmFHII, fumarate hydratase, lyase
Deposited on 2019-08-26, released 2020-09-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fumarate hydratase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_158240
    Database cross-references and differences (RAF-indexed):
    • PDB 6U4O
    Domains in SCOPe 2.07: d6u4oa_
  • Chain 'B':
    Compound: Fumarate hydratase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_158240
    Database cross-references and differences (RAF-indexed):
    • PDB 6U4O
    Domains in SCOPe 2.07: d6u4ob_
  • Chain 'C':
    Compound: Fumarate hydratase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_158240
    Database cross-references and differences (RAF-indexed):
    • PDB 6U4O
    Domains in SCOPe 2.07: d6u4oc_
  • Chain 'D':
    Compound: Fumarate hydratase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_158240
    Database cross-references and differences (RAF-indexed):
    • PDB 6U4O
    Domains in SCOPe 2.07: d6u4od_
  • Heterogens: LMR, GOL, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6u4oA (A:)
mletdsqrlrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamike
vaactnfklgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssr
aselidgsrssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlki
kmhefmnvikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavg
tglncskgfdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqls
gcfnttatalmrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvcl
qimgnhfttsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnreki
qeyvdkslmlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpme
mafphnnk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u4oA (A:)
rlrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamikevaactnf
klgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssraselidg
srssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlkikmhefmn
vikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavgtglncsk
gfdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqlsgcfntta
talmrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvclqimgnhf
ttsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnrekiqeyvdks
lmlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpmemafphn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6u4oB (B:)
mletdsqrlrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamike
vaactnfklgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssr
aselidgsrssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlki
kmhefmnvikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavg
tglncskgfdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqls
gcfnttatalmrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvcl
qimgnhfttsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnreki
qeyvdkslmlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpme
mafphnnk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u4oB (B:)
lrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamikevaactnfk
lgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssraselidgs
rssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlkikmhefmnv
ikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavgtglncskg
fdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqlsgcfnttat
almrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvclqimgnhft
tsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnrekiqeyvdksl
mlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpmemafphn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6u4oC (C:)
mletdsqrlrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamike
vaactnfklgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssr
aselidgsrssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlki
kmhefmnvikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavg
tglncskgfdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqls
gcfnttatalmrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvcl
qimgnhfttsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnreki
qeyvdkslmlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpme
mafphnnk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u4oC (C:)
lrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamikevaactnfk
lgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssraselidgs
rssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlkikmhefmnv
ikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavgtglncskg
fdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqlsgcfnttat
almrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvclqimgnhft
tsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnrekiqeyvdksl
mlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpmemafph

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6u4oD (D:)
mletdsqrlrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamike
vaactnfklgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssr
aselidgsrssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlki
kmhefmnvikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavg
tglncskgfdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqls
gcfnttatalmrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvcl
qimgnhfttsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnreki
qeyvdkslmlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpme
mafphnnk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u4oD (D:)
rlrvvedslgkinvpleryygaqtarslgnfnvctrsdtmplqivyslamikevaactnf
klgrissklsdaivkacrevyhgqhdnefplviwqtgsgtqtnmnvnevlssraselidg
srssrltvhpndhvnlgqssndifptamnlsiametawkvlpslnhlinvlkikmhefmn
vikigrthmqdavpmsvgqelsgyvsqlqqavdsiksqlplichlavggtavgtglncsk
gfdeelcvsltqltdrlyrtmykestpvvdlifkpaenkfaalaghdallqlsgcfntta
talmrlsndfcllssgpncglsefvlpanepgssimpgkvnptqceslrmvclqimgnhf
ttsmaasqgqlelnvckpliaanllhtcelltdstrcfadkcvrdlqlnrekiqeyvdks
lmlvtvltphigydlsaklvqhaskfkkglresaielnllcgekfdeivkpmemafph