PDB entry 6q92

View 6q92 on RCSB PDB site
Description: Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH
Class: hydrolase
Keywords: hydrolase inhibitor, borate, manganese cluster, pH-dependent, HYDROLASE
Deposited on 2018-12-17, released 2019-12-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arginase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ARG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6q92a1, d6q92a2
  • Chain 'B':
    Compound: Arginase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ARG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6q92b1, d6q92b2
  • Heterogens: ABH, MN, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6q92A (A:)
mgsshhhhhhssglvprgshmsaksrtigiigapfskgqprggveegptvlrkagllekl
keqecdvkdygdlpfadipndspfqivknprsvgkaseqlagkvaevkkngrislvlggd
hslaigsisgharvhpdlgviwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvp
gfswvtpcisakdivyiglrdvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyll
grkkrpihlsfdvdgldpsftpatgtpvvggltyreglyiteeiyktgllsgldimevnp
slgktpeevtrtvntavaitlacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >6q92A (A:)
saksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipnd
spfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgvi
wvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrd
vdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsft
patgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitl
acfglaregnhkpidyln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6q92B (B:)
mgsshhhhhhssglvprgshmsaksrtigiigapfskgqprggveegptvlrkagllekl
keqecdvkdygdlpfadipndspfqivknprsvgkaseqlagkvaevkkngrislvlggd
hslaigsisgharvhpdlgviwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvp
gfswvtpcisakdivyiglrdvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyll
grkkrpihlsfdvdgldpsftpatgtpvvggltyreglyiteeiyktgllsgldimevnp
slgktpeevtrtvntavaitlacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >6q92B (B:)
saksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipnd
spfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgvi
wvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrd
vdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsft
patgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitl
acfglaregnhkpidyln