PDB entry 6pxx

View 6pxx on RCSB PDB site
Description: Class D beta-lactamase in complex with beta-lactam antibiotic
Class: HYDROLASE/Antibiotic/Inhibitor
Keywords: Inhibitor, lactamase, HYDROLASE, HYDROLASE-Antibiotic-Inhibitor complex
Deposited on 2019-07-28, released 2019-10-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-10-09, with a file datestamp of 2019-10-04.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, KPE71T_00045
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XEC0 (Start-264)
      • engineered mutation (72)
    Domains in SCOPe 2.07: d6pxxa_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, KPE71T_00045
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XEC0 (Start-264)
      • engineered mutation (72)
    Domains in SCOPe 2.07: d6pxxb_
  • Heterogens: 5R7, EDO, CL, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pxxA (A:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfaipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxxA (A:)
ewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfaipnslialdl
gvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhafd
ygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangdy
iiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
ip

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pxxB (B:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfaipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxxB (B:)
akewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfaipnslial
dlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlha
fdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteang
dyiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqe
kiip