PDB entry 6pr6
View 6pr6 on RCSB PDB site
Description: S. aureus dihydrofolate reductase co-crystallized with para-tolyl-dihydropthalazine inhibitor and NADP(H)
Class: oxidoreductase/inhibitor
Keywords: dihydrofolate reductase, oxidoreductase-inhibitor complex
Deposited on
2019-07-10, released
2020-06-17
The last revision prior to the SCOPe 2.07 freeze date was dated
2020-06-17, with a file datestamp of
2020-06-12.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Staphylococcus aureus [TaxId:1280]
Gene: folA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6pr6a1, d6pr6a2 - Heterogens: OWS, NAP, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6pr6A (A:)
mtlsilvahdlqrvigfenqlpwhlpndlkhvkklstghtlvmgrktfesigkplpnrrn
vvltsdtsfnvegvdvihsiediyqlpghvfifggqtlfeemidkvddmyitviegkfrg
dtffppytfedwevassvegkldekntiphtflhlirkklvpr
Sequence, based on observed residues (ATOM records): (download)
>6pr6A (A:)
tlsilvahdlqrvigfenqlpwhlpndlkhvkklstghtlvmgrktfesigkplpnrrnv
vltsdtsfnvegvdvihsiediyqlpghvfifggqtlfeemidkvddmyitviegkfrgd
tffppytfedwevassvegkldekntiphtflhlirkklvpr