PDB entry 6p24

View 6p24 on RCSB PDB site
Description: Escherichia coli tRNA synthetase
Class: ligase
Keywords: Inhibitor, Aminoacyl-tRNA synthetase, PheRS, Antibacterial, LIGASE
Deposited on 2019-05-20, released 2020-11-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: XRAY
Resolution: 2.12 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phenylalanine--tRNA ligase alpha subunit
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: pheS, b1714, JW5277
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6p24a_
  • Chain 'B':
    Compound: Phenylalanine--tRNA ligase beta subunit
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: pheT, b1713, JW1703
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Phenylalanine--tRNA ligase alpha subunit
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: pheS, b1714, JW5277
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6p24c1, d6p24c2
  • Chain 'D':
    Compound: Phenylalanine--tRNA ligase beta subunit
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: pheT, b1713, JW1703
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, CL, HEZ, TRS, PEG, EDO, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6p24A (A:)
gshmasshlaelvasakaaisqasdvaaldnvrveylgkkghltlqmttlrelppeerpa
agavineakeqvqqalnarkaelesaalnarlaaetidvslpgrriengglhpvtrtidr
iesffgelgftvatgpeieddyhnfdalnipghhparadhdtfwfdttrllrtqtsgvqi
rtmkaqqppiriiapgrvyrndydqthtpmfhqmeglivdtnisftnlkgtlhdflrnff
eedlqirfrpsyfpftepsaevdvmgkngkwlevlgcgmvhpnvlrnvgidpevysgfaf
gmgmerltmlrygvtdlrsffendlrflkqfk

    Sequence, based on observed residues (ATOM records): (download) 
    >6p24A (A:)
laaetidvslpgrriengglhpvtrtidriesffgelgftvatgpeieddyhnfdalnip
ghhparadhdtfwfdttrllrtqtsgvqirtmkaqqppiriiapgrvyrndydqthtpmf
hqmeglivdtnisftnlkgtlhdflrnffeedlqirfrpsyfpftepsaevdvmgkngkw
levlgcgmvhpnvlrnvgidpevysgfafgmgmerltmlrygvtdlrsffendlrflkqf
k

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6p24C (C:)
gshmasshlaelvasakaaisqasdvaaldnvrveylgkkghltlqmttlrelppeerpa
agavineakeqvqqalnarkaelesaalnarlaaetidvslpgrriengglhpvtrtidr
iesffgelgftvatgpeieddyhnfdalnipghhparadhdtfwfdttrllrtqtsgvqi
rtmkaqqppiriiapgrvyrndydqthtpmfhqmeglivdtnisftnlkgtlhdflrnff
eedlqirfrpsyfpftepsaevdvmgkngkwlevlgcgmvhpnvlrnvgidpevysgfaf
gmgmerltmlrygvtdlrsffendlrflkqfk

    Sequence, based on observed residues (ATOM records): (download) 
    >6p24C (C:)
aelvasakaaisqasdvaaldnvrveylgkkghltlqmttlrelppeerpaagavineak
eqvqqalnarkaelesaalnarlaaetidvslpgrriengglhpvtrtidriesffgelg
ftvatgpeieddyhnfdalnipghhparadhdtfwfdttrllrtqtsgvqirtmkaqqpp
iriiapgrvyrndydqthtpmfhqmeglivdtnisftnlkgtlhdflrnffeedlqirfr
psyfpftepsaevdvmgkngkwlevlgcgmvhpnvlrnvgidpevysgfafgmgmerltm
lrygvtdlrsffendlrflkqfk

  • Chain 'D':
    No sequence available.