PDB entry 6oa6

View 6oa6 on RCSB PDB site
Description: crystal structure of the actin-binding domain of human alpha-actinin-4
Class: structural protein
Keywords: calponin homology domain, ch domain, structural protein, actin- binding protein, actin-crosslinking, glomeruloscleros spectrin family, disease mutation, nucleus, phosphorylation
Deposited on 2019-03-15, released 2020-03-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 1.37 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-actinin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTN4
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43707 (8-232)
      • expression tag (6-7)
      • engineered mutation (120)
    Domains in SCOPe 2.07: d6oa6a1, d6oa6a2, d6oa6a3
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6oa6A (A:)
    ggamdpefawekqqrktftawcnshlrkagtqienidedfrdglklmlllevisgerlpk
    pergkmrvhkinnvnkaldfiaskgvklvsigaeeivdgnakmtlgmiwtiilrfaiqdi
    dveetsakeglllwcqrktapyknvnvqnfhiswkdglafnalihrhrpelieydklrkd
    dpvtnlnnafevaekyldipkmldaedivntarpdekaimtyvssfyhafsgal
    

    Sequence, based on observed residues (ATOM records): (download)
    >6oa6A (A:)
    efawekqqrktftawcnshlrkagtqienidedfrdglklmlllevisgerlpkpergkm
    rvhkinnvnkaldfiaskgvklvsigaeeivdgnakmtlgmiwtiilrfaiqdidveets
    akeglllwcqrktapyknvnvqnfhiswkdglafnalihrhrpelieydklrkddpvtnl
    nnafevaekyldipkmldaedivntarpdekaimtyvssfyhafsga