PDB entry 6ey2

View 6ey2 on RCSB PDB site
Description: Crystal structure of XIAP-BIR3 in complex with a cIAP1-selective SM
Class: signaling protein
Keywords: Zinc finger motif, smac-mimetic, protein-ligand complex, BIR domain, signaling protein
Deposited on 2017-11-10, released 2018-08-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-08, with a file datestamp of 2018-08-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2a_
  • Chain 'B':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2b_
  • Chain 'C':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2c_
  • Chain 'D':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2d_
  • Chain 'E':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2e_
  • Chain 'F':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2f_
  • Chain 'G':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2g_
  • Chain 'H':
    Compound: E3 ubiquitin-protein ligase XIAP
    Species: Homo sapiens [TaxId:9606]
    Gene: XIAP, API3, BIRC4, IAP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ey2h_
  • Heterogens: ZN, C3T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ey2A (A:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2A (A:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleecl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ey2B (B:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2B (B:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleec

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ey2C (C:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2C (C:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleecl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ey2D (D:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2D (D:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleeclvr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6ey2E (E:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2E (E:)
stnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkp
sedpweqhakwypgckylleqkgqeyinnihlthsleecl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6ey2F (F:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2F (F:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleeclvr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6ey2G (G:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2G (G:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleeclv

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6ey2H (H:)
hhhhhhssglvprgshmasmtggqqmgrgssdavssdrnfpnstnlprnpsmadyearif
tfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsedpweqhakwypgckyl
leqkgqeyinnihlthsleeclvrtt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ey2H (H:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleecl