PDB entry 6ed7

View 6ed7 on RCSB PDB site
Description: Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772
Class: transferase/antibiotic
Keywords: Inhibitor adduct complex, ANTIBIOTIC, TRANSFERASE-ANTIBIOTIC complex
Deposited on 2018-08-08, released 2019-08-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-08-21, with a file datestamp of 2019-08-16.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7a1, d6ed7a2
  • Chain 'B':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7b1, d6ed7b2
  • Chain 'C':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7c1, d6ed7c2
  • Chain 'D':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7d1, d6ed7d2
  • Chain 'E':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7e1, d6ed7e2
  • Chain 'F':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7f1, d6ed7f2
  • Chain 'G':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7g1, d6ed7g2
  • Chain 'H':
    Compound: 7,8-diamino-pelargonic acid aminotransferase
    Species: Escherichia coli [TaxId:562]
    Gene: bioA, EL75_3021, EL79_3111, EL80_3072
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ed7h1, d6ed7h2
  • Heterogens: PLP, J4J, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7A (A:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7B (B:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7C (C:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7D (D:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7E (E:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7F (F:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7G (G:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ed7H (H:)
attddlafdqrhiwhpytsmtsplpvypvvsaegcelilsdgrrlvdgmsswwaaihgyn
hpqlnaamksqidamshvmfggithapaielcrklvamtpqplecvfladsgsvavevam
kmalqywqakgearqrfltfrngyhgdtfgamsvcdpdnsmhslwkgylpenlfapapqs
rmdgewderdmvgfarlmaahrheiaaviiepivqgaggmrmyhpewlkrirkicdregi
lliadeiatgfgrtgklfacehaeiapdilclgkaltggtmtlsatlttrevaetisnge
agcfmhgptfmgnplacaaanaslailesgdwqqqvadievqlreqlapardaemvadvr
vlgaigvvetthpvnmaalqkffveqgvwirpfgkliylmppyiilpqqlqrltaavnra
vqdetffcq