PDB entry 6e5s

View 6e5s on RCSB PDB site
Description: Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II
Class: lipid binding protein
Keywords: Retinol, iLBP, Protein Switch, CYTOSOLIC PROTEIN, LIPID BINDING PROTEIN
Deposited on 2018-07-22, released 2019-07-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sa_
  • Chain 'B':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sb_
  • Chain 'C':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sc_
  • Chain 'D':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sd_
  • Chain 'E':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5se_
  • Chain 'F':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sf_
  • Chain 'G':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sg_
  • Chain 'H':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sh_
  • Chain 'I':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5si_
  • Chain 'J':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sj_
  • Chain 'K':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sk_
  • Chain 'L':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (50)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d6e5sl_
  • Heterogens: RET, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sA (A:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sB (B:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sC (C:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sD (D:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sE (E:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sF (F:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sG (G:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sH (H:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sI (I:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sJ (J:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sK (K:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6e5sL (L:)
trdqngtwemesnenfegymkaldidfatrkiavrltqtkvidqdgdnfkdkttstfrny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk