PDB entry 6dvn

View 6dvn on RCSB PDB site
Description: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-137
Class: hydrolase/hydrolase inhibitor
Keywords: Histone deacetylase, metallohydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2018-06-24, released 2018-08-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dvna_
  • Chain 'B':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dvnb_
  • Chain 'C':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dvnc_
  • Chain 'D':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dvnd_
  • Heterogens: ZN, K, HB7, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6dvnA (A:)
snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
sslr

    Sequence, based on observed residues (ATOM records): (download) 
    >6dvnA (A:)
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6dvnB (B:)
snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
sslr

    Sequence, based on observed residues (ATOM records): (download) 
    >6dvnB (B:)
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6dvnC (C:)
snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
sslr

    Sequence, based on observed residues (ATOM records): (download) 
    >6dvnC (C:)
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6dvnD (D:)
snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
sslr

    Sequence, based on observed residues (ATOM records): (download) 
    >6dvnD (D:)
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr