PDB entry 6cqa

View 6cqa on RCSB PDB site
Description: E. coli DHFR complex with inhibitor AMPQD
Class: oxidoreductase
Keywords: DHFR, dihydrofolate reductase, inhibitor, complex, OXIDOREDUCTASE
Deposited on 2018-03-14, released 2019-01-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-09, with a file datestamp of 2019-01-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: folA, tmrA, b0048, JW0047
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6cqaa_
  • Heterogens: PQD, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6cqaA (A:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerrhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6cqaA (A:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr