PDB entry 6blx

View 6blx on RCSB PDB site
Description: Crystal structure of IAg7 in complex with insulin mimotope p8G9E
Class: immune system
Keywords: TYPE 1 DIABETES, T cell autoimmunity, MHC classII, IMMUNE SYSTEM
Deposited on 2017-11-11, released 2017-12-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: H-2 class II histocompatibility antigen, A-D alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Aa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6blxa1, d6blxa2
  • Chain 'B':
    Compound: H2-Ab1 protein
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Ab1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q31135 (27-End)
      • see remark 999 (0-12)
      • linker (13-14)
      • linker (25-26)
  • Heterogens: NAG, EDO, FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6blxA (A:)
    dieadhvgfygttvyqspgdigqythefdgdelfyvdldkkktvwrlpefgqlilfepqg
    glqniaaekhnlgiltkrsnftpatneapqatvfpkspvllgqpntlicfvdnifppvin
    itwlrnsksvtdgvyetsflvnrdhsfhklsyltfipsdddiydckvehwgleepvlkhw
    epe
    

    Sequence, based on observed residues (ATOM records): (download)
    >6blxA (A:)
    dieadhvgfygttvyqspgdigqythefdgdelfyvdldkkktvwrlpefgqlilfepqg
    glqniaaekhnlgiltkrsnftpatneapqatvfpkspvllgqpntlicfvdnifppvin
    itwlrnsksvtdgvyetsflvnrdhsfhklsyltfipsdddiydckvehwgleepvlkhw
    ep
    

  • Chain 'B':
    No sequence available.