PDB entry 6b1x

View 6b1x on RCSB PDB site
Description: Crystal structure KPC-2 beta-lactamase complexed with WCK 5153 by soaking
Class: HYDROLASE/HYDROLASE Inhibitor
Keywords: Inhibitor, complex, HYDROLASE, HYDROLASE-HYDROLASE Inhibitor complex
Deposited on 2017-09-19, released 2018-08-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-01, with a file datestamp of 2018-07-27.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbapenem-hydrolyzing beta-lactamase KPC
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla, kpc, kpc1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b1xa_
  • Chain 'B':
    Compound: Carbapenem-hydrolyzing beta-lactamase KPC
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla, kpc, kpc1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b1xb_
  • Heterogens: C9D, CIT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6b1xA (A:)
ataltnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavla
rsqqqaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkel
ggpagltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaap
qrqqfvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlav
ytrapnkddkhseaviaaaarlaleglg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6b1xB (B:)
ataltnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavla
rsqqqaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkel
ggpagltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaap
qrqqfvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlav
ytrapnkddkhseaviaaaarlaleglg

    Sequence, based on observed residues (ATOM records): (download) 
    >6b1xB (B:)
ltnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsq
qqaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggp
agltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrq
qfvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytr
apnkddkhseaviaaaarlaleglg