PDB entry 6agl

View 6agl on RCSB PDB site
Description: Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli
Class: biosynthetic protein
Keywords: 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (DAHP synthase), Escherichia coli, aromatic amino acid biosynthesis, feedback inhibition, allosteric regulation., BIOSYNTHETIC PROTEIN
Deposited on 2018-08-13, released 2019-04-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-04-17, with a file datestamp of 2019-04-12.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: aroF, b2601, JW2582
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6agla_
  • Chain 'B':
    Compound: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: aroF, b2601, JW2582
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6aglb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6aglA (A:)
mqkdalnnvhitdeqvlmtpeqlkaafplslqqeaqiadsrksisdiiagrdprllvvcg
pcsihdpetaleyarrfkalaaevsdslylvmrvyfekprttvgwkglindphmdgsfdv
eaglqiarklllelvnmglplatealdpnspqylgdlfswsaigarttesqthremasgl
smpvgfkngtdgslatainamraaaqphrfvginqagqvallqtqgnpdghvilrggkap
nyspadvaqcekemeqaglrpslmvdcshgnsnkdyrrqpavaesvvaqikdgnrsiigl
miesnihegnqsseqprsemkygvsvtdaciswemtdallreihqdlngqltarva

    Sequence, based on observed residues (ATOM records): (download) 
    >6aglA (A:)
hitdeqvlmtpeqlkaafplslqqeaqiadsrksisdiiagrdprllvvcgpcsihdpet
aleyarrfkalaaevsdslylvmrvyfekpgwkglindphmdgsfdveaglqiarkllle
lvnmglplatealdpnspqylgdlfswsaigarttesqthremasglsmpvgfkngtdgs
latainamraaaqphrfvginqagqvallqtqgnpdghvilrggkapnyspadvaqceke
meqaglrpslmvdcshgnsnkdyrrqpavaesvvaqikdgnrsiiglmiesnihegtdac
iswemtdallreihqdlngq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6aglB (B:)
mqkdalnnvhitdeqvlmtpeqlkaafplslqqeaqiadsrksisdiiagrdprllvvcg
pcsihdpetaleyarrfkalaaevsdslylvmrvyfekprttvgwkglindphmdgsfdv
eaglqiarklllelvnmglplatealdpnspqylgdlfswsaigarttesqthremasgl
smpvgfkngtdgslatainamraaaqphrfvginqagqvallqtqgnpdghvilrggkap
nyspadvaqcekemeqaglrpslmvdcshgnsnkdyrrqpavaesvvaqikdgnrsiigl
miesnihegnqsseqprsemkygvsvtdaciswemtdallreihqdlngqltarva

    Sequence, based on observed residues (ATOM records): (download) 
    >6aglB (B:)
hitdeqvlmtpeqlkaafplslqqeaqiadsrksisdiiagrdprllvvcgpcsihdpet
aleyarrfkalaaevsdslylvmrvyfekpgwkglindphmdgsfdveaglqiarkllle
lvnmglplatealdpnspqylgdlfswsaigarttesqthremasglsmpvgfkngtdgs
latainamraaaqphrfvginqagqvallqtqgnpdghvilrggkapnyspadvaqceke
meqaglrpslmvdcshgnsnkdyrrqpavaesvvaqikdgnrsiiglmiesnihegtdac
iswemtdallreihqdlngq