PDB entry 5zec

View 5zec on RCSB PDB site
Description: Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (Q136N/F161V/S196G/E214G/S237C)
Class: isomerase
Keywords: Alcohol dehydrogenase(KpADH), NADPH, ISOMERASE
Deposited on 2018-02-27, released 2019-01-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-02, with a file datestamp of 2018-12-28.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uncharacterized protein ADH
    Species: Vanderwaltozyma polyspora DSM 70294 [TaxId:436907]
    Gene: Kpol_529p27
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7TM80 (0-341)
      • engineered mutation (135)
      • engineered mutation (160)
      • engineered mutation (195)
      • engineered mutation (213)
      • engineered mutation (236)
    Domains in SCOPe 2.07: d5zeca_
  • Chain 'B':
    Compound: Uncharacterized protein ADH
    Species: Vanderwaltozyma polyspora DSM 70294 [TaxId:436907]
    Gene: Kpol_529p27
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7TM80 (0-341)
      • engineered mutation (135)
      • engineered mutation (160)
      • engineered mutation (195)
      • engineered mutation (213)
      • engineered mutation (236)
    Domains in SCOPe 2.07: d5zecb_
  • Heterogens: NAP, EDO, PEG, IPA, GOL, EOH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5zecA (A:)
msvlisgasgyiakhivrvlleqnykvigtvrsqdkadkllkqynnpnlsyeivpeianl
dafddifkkhgkeikyvihaaspvnfgakdlekdlvipaingtknmfeaikkyapdtver
vvmtasyasimtphrnndptltldeetwnpvteenayenvvtaycasktfaekeawkfvk
ensdavkfklttihpgfvfgpqnfdedvtkklngtceiingllhapfdtkvekthfcqfi
dvrdvakthvlgfqkdelinqrlllcngafsqqdivnvfnedfpelkgqfppedkdtdln
kgvtgckidnektkkllafeftpfhktihdtvyqilhkegrv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5zecB (B:)
msvlisgasgyiakhivrvlleqnykvigtvrsqdkadkllkqynnpnlsyeivpeianl
dafddifkkhgkeikyvihaaspvnfgakdlekdlvipaingtknmfeaikkyapdtver
vvmtasyasimtphrnndptltldeetwnpvteenayenvvtaycasktfaekeawkfvk
ensdavkfklttihpgfvfgpqnfdedvtkklngtceiingllhapfdtkvekthfcqfi
dvrdvakthvlgfqkdelinqrlllcngafsqqdivnvfnedfpelkgqfppedkdtdln
kgvtgckidnektkkllafeftpfhktihdtvyqilhkegrv