PDB entry 5wxs
View 5wxs on RCSB PDB site
Description: Crystal structure of uPA in complex with S2444
Class: hydrolase/hydrolase inhibitor
Keywords: Serine proteases, uPA, pepetide inhibitors, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2017-01-08, released
2018-07-11
The last revision prior to the SCOPe 2.07 freeze date was dated
2018-07-11, with a file datestamp of
2018-07-06.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'U':
Compound: urokinase-type plasminogen activator chain b
Species: Homo sapiens [TaxId:9606]
Gene: PLAU
Database cross-references and differences (RAF-indexed):
- Uniprot P00749 (0-End)
- engineered mutation (120)
- engineered mutation (143)
Domains in SCOPe 2.07: d5wxsu_ - Heterogens: 7YF, HOH
PDB Chain Sequences:
- Chain 'U':
Sequence, based on SEQRES records: (download)
>5wxsU (U:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkeenglal
Sequence, based on observed residues (ATOM records): (download)
>5wxsU (U:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtk