PDB entry 5sag

View 5sag on RCSB PDB site
Description: PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NendoU in complex with EN300-1605072
Class: HYDROLASE/HYDROLASE inhibitor
Keywords: SGC - Diamond I04-1 fragment screening, PanDDA, XChemExplorer, nsp15, nendoU, sars-cov-2, sars, covid, covid19, HYDROLASE-HYDROLASE inhibitor complex
Deposited on 2021-05-19, released 2021-06-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-09, with a file datestamp of 2021-06-04.
Experiment type: XRAY
Resolution: 1.88 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-348)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d5saga1, d5saga2, d5saga3
  • Chain 'B':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-348)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d5sagb1, d5sagb2, d5sagb3
  • Heterogens: ZQG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5sagA (A:)
gamslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafel
wakrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkptetica
pltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfn
yykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivy
gdfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidl
llddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >5sagA (A:)
amslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5sagB (B:)
gamslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafel
wakrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkptetica
pltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfn
yykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivy
gdfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidl
llddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >5sagB (B:)
amslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq