PDB entry 5s72

View 5s72 on RCSB PDB site
Description: PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NendoU in complex with BBL029427
Class: hydrolase
Keywords: SGC - Diamond I04-1 fragment screening, PanDDA, XChemExplorer, nsp15, nendoU, sars-cov-2, sars, covid, covid19, HYDROLASE
Deposited on 2020-11-13, released 2020-11-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-348)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d5s72a1, d5s72a2, d5s72a3
  • Chain 'B':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-348)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d5s72b1, d5s72b2, d5s72b3
  • Heterogens: WUY, CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5s72A (A:)
gamslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafel
wakrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkptetica
pltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfn
yykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivy
gdfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidl
llddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >5s72A (A:)
amslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5s72B (B:)
gamslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafel
wakrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkptetica
pltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfn
yykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivy
gdfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidl
llddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >5s72B (B:)
amslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq